Laron dwarfism is due to abnormal GH receptors and not a deficiency in growth hormone.

Question

Quizplus · Accepted Answer

Laron dwarfism, also known as growth hormone insensitivity syndrome, is caused by mutations in the gene that codes for the GH receptor. This leads to a reduced ability of cells to respond to GH, even if there is an adequate amount of hormone present. As a result, affected individuals experience growth failure and develop features characteristic of dwarfism, despite normal or elevated GH levels. Therefore, the condition is not characterized by a deficiency of GH, but rather by a resistance to its actions.

Laron Dwarfism Is Due to Abnormal GH Receptors and Not