A systemic disorder that increases the uric acid content of the blood and may cause a joint condition that commonly affects the feet (particularly the joints of the great toe)is called:

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Gout is a systemic disorder that increases the uric acid content of the blood and can cause a joint condition that commonly affects the feet, particularly the joints of the great toe. Osteoarthritis, rheumatoid arthritis, and osteoporosis are all conditions that affect the joints, but they are not specifically associated with increased uric acid levels.

A Systemic Disorder That Increases the Uric Acid Content of the Blood