B lymphocytes develop immunocompetence in the ________.

Name: B lymphocytes develop immunocompetence in the ________.
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B lymphocytes are responsible for humoral immunity, and they arise and develop their immunocompetence in the bone marrow. This is where they undergo rearrangement of their B-cell receptor genes and undergo selection for self-tolerance. The other options, thymus, spleen, and lymph nodes, are involved in the development and maturation of T cells, not B cells.

B Lymphocytes Develop Immunocompetence in the ________