What determines where bone matrix will be remodeled?
A) sex hormones
B) osteoblasts and osteoclasts
C) the pull of gravity and muscles on the skeleton and calcium ion levels in the blood
D) parathyroid hormone (PTH) and calcitonin
E) sodium ion levels in the blood

Question

Quizplus · Accepted Answer

The pull of gravity and muscles on the skeleton and calcium ion levels in the blood determine where bone matrix will be remodeled. This is known as Wolff's law, which states that bone tissue adapts to the loads under which it is placed. Additionally, calcium ion levels in the blood play a role in bone remodeling because osteoclasts will dissolve bone matrix to release calcium ions into the bloodstream when calcium levels are low, while osteoblasts will build new bone matrix when calcium levels are high. The other options, such as sex hormones, PTH and calcitonin, and sodium ion levels, may affect bone health and metabolism but do not determine where bone matrix is remodeled.

What Determines Where Bone Matrix Will Be Remodeled