What are the two major physical changes in the brain that are characteristic of Alzheimer's disease?
A) aluminum deposition and edema
B) amyloid plaques and neurofibrillary tangles
C) amyloid plaques and hypertrophy
D) calcification and hypertrophy
E) aluminum deposition and neurofibrillary tangles

Question

Quizplus · Accepted Answer

The two major physical changes in the brain that are characteristic of Alzheimer's disease are amyloid plaques and neurofibrillary tangles. Amyloid plaques are abnormal clumps of protein fragments that accumulate between nerve cells in the brain, while neurofibrillary tangles are twisted fibers of a protein called tau that build up inside nerve cells. These changes ultimately lead to the death of nerve cells and a progressive decline in cognitive function.

What Are the Two Major Physical Changes in the Brain