In holocarboxylase synthetase deficiency, what vitamin supplement is used as treatment and to prevent serious complications?

Question

In holocarboxylase synthetase deficiency, what vitamin supplement is used as treatment and to prevent serious complications?​

Quizplus · Accepted Answer

Holocarboxylase synthetase deficiency results in impaired activation of biotin-dependent carboxylase enzymes leading to metabolic abnormalities. Treatment and prevention of serious complications involve high doses of oral biotin supplementation. Thiamin, riboflavin, niacin, and folic acid do not play a role in the treatment of this condition.

In Holocarboxylase Synthetase Deficiency, What Vitamin Supplement Is Used as Treatment