Abnormal chromosomes are frequently found in malignant tumours. Errors such as translocations may place a gene in close proximity to different control regions. Which of the following might then occur to make the cancer worse?
A)an increase in nondisjunction
B)expression of inappropriate gene products
C)a decrease in mitotic frequency
D)death of the cancer cells in the tumour
E)sensitivity of the immune system

Question

Quizplus · Accepted Answer

The translocation might lead to the expression of inappropriate gene products, which could promote the growth of cancer cells and make the cancer worse. A) An increase in nondisjunction is the failure of chromosomes to properly separate during cell division, causing abnormal chromosome numbers in daughter cells, but it is not directly related to the translocation. C) A decrease in mitotic frequency would slow down cell division, which may actually inhibit cancer growth. D) Death of cancer cells in the tumor would be desirable, but it does not address the question of how the translocation could make the cancer worse. E) Sensitivity of the immune system is not directly related to the translocation.

Abnormal Chromosomes Are Frequently Found in Malignant Tumours