In large-scale, genome-wide association studies in humans, correlation is sought between
A)lengthy sequences that might be shared by most members of a population.
B)single nucleotide polymorphisms found only in persons with a particular disorder.
C)single nucleotide polymorphisms found in families with a particular intronsequence.
D)single nucleotide polymorphisms in two or more adjacent genes.
E)large inversions that displace the centromere.

Question

Quizplus · Accepted Answer

Genome-wide association studies in humans typically look for correlations between single nucleotide polymorphisms (SNPs) and a particular disorder or trait. Therefore, the best choice is B, which describes SNPs found only in persons with a particular disorder. The other options are either too general (A) or too specific (C, D, E) to accurately describe the goal of genome-wide association studies.

In Large-Scale, Genome-Wide Association Studies in Humans, Correlation Is Sought