A nonfunctional CD4 protein on a helper T cell would result in the helper T cell being unable to
A)respond to T-independent antigens.
B)lyse tumour cells.
C)stimulate a cytotoxic T cell.
D)interact with a class I MHC-antigen complex.
E)interact with a class II MHC-antigen complex.

Question

Quizplus · Accepted Answer

The CD4 protein on a helper T cell binds to class II MHC-antigen complex on antigen-presenting cells (APCs) and facilitates the activation of the T cell, leading to the production of cytokines that stimulate B cells and cytotoxic T cells. Without functioning CD4 protein, the helper T cell would not be able to interact with class II MHC-antigen complex on APCs, resulting in impaired immune response.

A Nonfunctional CD4 Protein on a Helper T Cell Would