Some nonsteroid hormones do not use a second messenger but are taken into the cell by endocytosis and act directly on their target cells.

Name: Some nonsteroid hormones do not use a second messenger but are taken into the cell by endocytosis and act directly on their target cells.
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Nonsteroid hormones typically act through second messenger systems and do not enter the cell directly. They bind to receptors on the cell surface, which then triggers a cascade of intracellular events.

Some Nonsteroid Hormones Do Not Use a Second Messenger but Are