Hemoglobin's affinity for oxygen when the BPG level is high is
A)greater than hemoglobin's affinity for oxygen when the BPG level is low.
B)less than hemoglobin's affinity for oxygen when the BPG level is low.
C)equal to hemoglobin's affinity for oxygen when the BPG level is low.
D)equal to hemoglobin's affinity for oxygen when pH is low.
E)None of the answers is correct.

Question

Quizplus · Accepted Answer

High levels of 2,3-BPG (also referred to as BPG) result in a decrease in the affinity of hemoglobin for oxygen, known as the Bohr effect, which is a way to unload oxygen in tissues that have high metabolic needs. This is because BPG binds to hemoglobin and stabilizes the T state, resulting in decreased oxygen binding to the heme groups. Therefore, Option B is the correct answer as hemoglobin's affinity for oxygen is less when there are high levels of BPG.

Hemoglobin's Affinity for Oxygen When the BPG Level Is High