In the general activation syndrome (GAS), described by Selye, during the exhaustion stage:

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During the exhaustion stage of GAS, the stress reaction becomes more and more maladaptive. This stage occurs after prolonged exposure to stressors, and the body's resources become depleted, resulting in various physical and psychological changes. These changes can include fatigue, decreased immunity, and increased susceptibility to illness. Hence, the stress reaction during this stage is generally considered to be maladaptive.

In the General Activation Syndrome (GAS), Described by Selye, During