What was the most difficult issue faced by the framers of the Constitution?

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Slavery was a deeply controversial and divisive issue during the Constitutional Convention. Many delegates from northern states wanted to abolish slavery, while delegates from southern states wanted to protect their right to own slaves. This issue ultimately led to the Three-Fifths Compromise and the inclusion of a Fugitive Slave Clause in the Constitution.

What Was the Most Difficult Issue Faced by the Framers