Increased Activity of the Neurotransmitter Dopamine at Synapses in the Mesolimbic

Increased activity of the neurotransmitter dopamine at synapses in the mesolimbic dopamine system is known to cause euphoria.Therefore, a good strategy for the development of new euphoriants is to develop drugs that:

A) Inhibit the sodium cotransporter for dopamine in the nerve terminal.
B) Inhibit the transporter that pumps dopamine into synaptic vesicles.
C) Inhibit tyrosine hydroxylase.
D) Induce enhanced expression of catechol-O-methyltransferase (COMT) .
E) Block voltage-gated calcium channels in the nerve terminals.