Some Hormones Act by Triggering the Release of Calcium from the ER.These

Some hormones act by triggering the release of calcium from the ER.These hormones can regulate gene expression, usually by:

A) The binding of calcium to transcription factors, which in turn bind to promoters and enhancers of genes.
B) The activation of calmodulin-regulated protein kinases that phosphorylate nuclear transcription factors.
C) The direct binding of calcium to the DNA double helix.
D) The methylation of DNA in the promoters and enhancers of genes by a calcium-dependent enzyme.
E) The binding of calcium to mRNA, which stabilizes the RNA against the action of RNA-degrading enzymes.