The nurse is administering medications to a patient who is in liver failure due to end-stage cirrhosis.The nurse is aware that patients with liver failure are most likely to have problems with which pharmacokinetic phase?

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The liver is the organ that is most responsible for drug metabolism.Decreased liver function will most affect a drug's metabolism.The absorption of a drug is not affected by liver function,and distribution is not affected by liver function.Excretion is affected only because decreased liver function may not transform drugs into water-soluble substances for elimination via the kidneys,but this is not the best answer to this question.

The Nurse Is Administering Medications to a Patient Who Is