During the development of a new drug by a pharmaceutical company,the researcher must ensure that the participants in experimental drug studies do not have unrealistic expectations of the new drug's usefulness.To prevent any bias that may occur,the researcher designs the study to include which of the following?

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To prevent bias that may occur as a result of unrealistic expectations of an investigational new drug,a placebo is incorporated into the study.
Health Canada approval,if given,does not occur until after phase III.Informed consent is required in all drug studies.Efficacy information is not determined until the study is underway.

During the Development of a New Drug by a Pharmaceutical