Which of the Following Statements Is True Regarding Loop Diuretics

Which of the following statements is true regarding loop diuretics?

A) They are also called aldosterone-inhibiting diuretics.
B) They are very potent,providing a diuretic effect that lasts at least 6 hours.
C) They are particularly useful when rapid diuresis is desired because their onset of action is rapid.
D) They have the disadvantage of ceasing to be effective when the creatinine clearance decreases below 25 mL/min.