A patient who takes an oral sulfonylurea medication will begin taking fluconazole (Diflucan). The nurse will expect to monitor which lab values in this patient?

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Fluconazole can increase the hypoglycemic effects of sulfonylureas, which can result in low blood sugar levels. Therefore, the nurse should monitor the patient's glucose levels closely. Monitoring BUN and creatinine may be warranted if the patient has pre-existing renal impairment or is at risk for renal impairment. Electrolyte monitoring may also be needed, but not specifically because of the interaction between sulfonylureas and fluconazole. There is no need to monitor fluconazole levels, as therapeutic drug monitoring is not necessary for this medication.

A Patient Who Takes an Oral Sulfonylurea Medication Will Begin