Which component of the BM stroma is responsible for the formation of the ECM?

Question

Quizplus · Accepted Answer

Fibroblasts are the main cellular component of the BM stroma responsible for producing and secreting extracellular matrix (ECM) proteins such as collagens, fibronectin, and laminin. Other cells in the BM stroma such as osteoblasts and osteoclasts are mainly involved in bone formation and resorption, respectively, and cytokines are signaling molecules involved in immune regulation and inflammation.

Which Component of the BM Stroma Is Responsible for the Formation