Which of the following "marks" the RBC as senescent?

Question

Quizplus · Accepted Answer

A cluster of band 3 proteins on the RBC membrane marks the RBC as senescent. This cluster is recognized by macrophages in the spleen, leading to phagocytosis of the senescent RBC. Denatured hemoglobin on the RBC membrane (B) is not a reliable marker of senescence, as it can also be present on RBCs undergoing hemolysis. An elongated RBC (C) may indicate a problem with the cell's shape or function, but it is not specifically associated with senescence. Hyperphosphorylation of integral proteins (D) is not a known marker of RBC senescence.

Which of the Following "Marks" the RBC as Senescent