High concentrations of heme would cause which of the following?
A) A decrease in the synthesis of ALA
B) An increase in globin chain production
C) A decrease in globin chain production
D) An increase in ferrochelatase

Question

Quizplus · Accepted Answer

High concentrations of heme lead to a decrease in the synthesis of ALA (aminolevulinic acid) because heme acts as a negative feedback inhibitor on the enzyme ALA synthase, which is the rate-limiting step in the synthesis of heme. This mechanism helps regulate heme concentration within the cell.

High Concentrations of Heme Would Cause Which of the Following