Which of the following peripheral blood pictures is likely to be seen if elevated levels of GM-CSF persist in the bone marrow?
A) Monocytosis, neutropenia
B) Neutrophilia, eosinophilia
C) Monocytopenia, granulocytosis
D) Granulocytosis, monocytosis

Question

Quizplus · Accepted Answer

GM-CSF (granulocyte-macrophage colony-stimulating factor) is a cytokine that stimulates the production and differentiation of granulocytes and monocytes in the bone marrow. Therefore, the likely peripheral blood picture in the case of elevated levels of GM-CSF would be granulocytosis (increased number of granulocytes) and monocytosis (increased number of monocytes).

Which of the Following Peripheral Blood Pictures Is Likely to Be