An instrument printout indicates that a patient has an RPI of 1.3, hemoglobin of 7 g/dL, and MCV of 112 fl. What can be concluded from this?
A) There is acute hemolysis present.
B) This is the result of iron deficiency.
C) The anemia is associated with renal disease.
D) There could be a nuclear maturation defect.

Question

Quizplus · Accepted Answer

The RPI (reticulocyte production index) of 1.3 suggests inadequate bone marrow response for the degree of anemia (hemoglobin of 7 g/dL), and an MCV (mean corpuscular volume) of 112 fl indicates macrocytosis. These findings are consistent with a nuclear maturation defect, such as megaloblastic anemia, which can be caused by vitamin B12 or folate deficiency.

An Instrument Printout Indicates That a Patient Has an RPI