PK deficiency causes which of the following to occur in the erythrocyte?
A) Denatured hemoglobin to precipitate
B) Splenic sequestration of normal erythrocytes
C) Premature apoptosis from lack of ATP formed
D) Membrane instability with excessive sodium and calcium influx

Question

Quizplus · Accepted Answer

PK (pyruvate kinase) deficiency leads to decreased ATP production, causing membrane instability and resulting in excessive sodium and calcium influx in erythrocytes.

PK Deficiency Causes Which of the Following to Occur in the Erythrocyte