A patient presents with a leukocyte count of 120 × 10⁹/L and splenomegaly.The blood smear reveals a shift to the left with promyelocytes and blasts.The platelets are increased,and the LAP is decreased.Which condition is associated with these results?

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The combination of leukocytosis with a left shift, increased platelets, decreased LAP, and splenomegaly is suggestive of chronic myeloid leukemia (CML). Promyelocytes and blasts are characteristic of the blast phase of CML. Bacterial infection may cause a left shift, but the platelet count and LAP are typically not increased. Reactive chronic neutrophilia and leukemoid reaction can cause leukocytosis with a left shift, but the platelet count and LAP are typically not increased, and splenomegaly is not a feature.

A Patient Presents with a Leukocyte Count of 120 ×