Which of the following indicates a reason for performing cytochemical staining on bone marrow specimens of suspected hematologic dyscrasias?
A) It has higher specificity for hematopoietic lineage differentiation than does standard morphology.
B) It has lower incidence of false negatives in detecting malignancies.
C) Manual differentials are prone to misinterpretation, whereas cytochemical staining is not.
D) It provides a better overview of bone marrow status of hematopoiesis than does the manual differential.

Question

Quizplus · Accepted Answer

Cytochemical staining is useful for determining the lineage of hematopoietic cells and is more specific than standard morphology. It can be used in conjunction with manual differentials to improve diagnostic accuracy. While it may have a lower incidence of false negatives than standard morphology, it is not free from misinterpretation. Additionally, it provides more detailed information on specific cell types, rather than an overview of bone marrow status as a whole.

Which of the Following Indicates a Reason for Performing Cytochemical