Thomas Jefferson was deeply concerned about the implications of the Missouri Compromise.

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Thomas Jefferson did express concern about the potential consequences of the Missouri Compromise, particularly regarding the issue of slavery and its expansion into new territories. He wrote several letters expressing his views on the matter, including one to John Holmes in 1820, where he stated that the compromise was a "fire bell in the night" and could lead to the eventual dissolution of the Union.

Thomas Jefferson Was Deeply Concerned About the Implications of the Missouri