Tropomyosin and troponin are often called stimulation proteins because of their role in covering or exposing the binding sites for cross-bridge interaction between actin and myosin.

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Tropomyosin and troponin are regulatory proteins that control the interaction between actin and myosin by covering or exposing the binding sites on actin, not stimulation proteins. They play a key role in muscle contraction by regulating the access of myosin to its binding sites on actin filaments, in response to calcium ion levels.

Tropomyosin and Troponin Are Often Called Stimulation Proteins Because of Their