Major neuropathological correlates of Alzheimer's disease are
A) neurofibrillary tangles in the neural cytoplasm.
B) amyloid plaques.
C) a selective decline in dopamine levels.
D) all of the above
E) both A and B

Question

Quizplus · Accepted Answer

The two major neuropathological correlates of Alzheimer's disease are neurofibrillary tangles (NFTs) and amyloid plaques. NFTs are abnormal structures that form inside neurons and consist of a protein called tau. Amyloid plaques are composed of beta-amyloid protein and are found between neurons. Therefore, option E, both A and B are the correct answer. Option C, a selective decline in dopamine levels, is associated with Parkinson's disease and not Alzheimer's disease. Option D, all of the above, is incorrect as option C is not a major neuropathological correlate of Alzheimer's disease.

Major Neuropathological Correlates of Alzheimer's Disease Are