The "high" experienced by cocaine users was found in one study to be related to the degree of binding of the cocaine to
A) dopamine transporters.
B) dopamine autoreceptors.
C) serotonergic receptors.
D) dopamine receptors.
E) nucleus accumbens neurons.

Question

Quizplus · Accepted Answer

The binding of cocaine to dopamine transporters prevents the reuptake of dopamine, leading to an accumulation of dopamine in the synaptic cleft, which results in a "high" sensation. Studies have shown a positive correlation between the degree of dopamine transporter binding and the intensity of the cocaine high experienced by users.

The "High" Experienced by Cocaine Users Was Found in One