Insights into the mechanisms of Alzheimer's disease have come from studying the relationship between Alzheimer's disease and
A) multiple sclerosis.
B) epilepsy.
C) Down syndrome.
D) kindling.
E) Parkinson's disease.

Question

Quizplus · Accepted Answer

Down syndrome is caused by having an extra copy of chromosome 21, which also contains the gene for beta-amyloid precursor protein (APP). People with Down syndrome have an increased risk of developing Alzheimer's disease because they produce more beta-amyloid, which can accumulate and form the plaques seen in Alzheimer's disease.

Answer: E
 Parkinson's disease and Alzheimer's disease both involve the accumulation of specific proteins in the brain. In Parkinson's disease, it is alpha-synuclein, while in Alzheimer's disease, it is beta-amyloid and tau proteins. Studying the similarities and differences between these two diseases can provide insights into the mechanisms of Alzheimer's.

Insights into the Mechanisms of Alzheimer's Disease Have Come from Studying