The induction of LTP at glutaminergic synapses appears to require
A) the depolarization of the postsynaptic neuron.
B) the depolarization of the presynaptic neuron.
C) an influx of calcium ions into the postsynaptic neuron.
D) both B and C
E) both A and C

Question

Quizplus · Accepted Answer

The induction of LTP at glutaminergic synapses requires depolarization of the postsynaptic neuron and an influx of calcium ions into the postsynaptic neuron. The depolarization of the postsynaptic neuron causes the opening of NMDA receptors, allowing calcium ions to enter the neuron. This influx of calcium ions is necessary for the molecular changes that lead to LTP. The depolarization of the presynaptic neuron (choice B) does not play a significant role in the induction of LTP at glutaminergic synapses.

The Induction of LTP at Glutaminergic Synapses Appears to Require