In functional brain-imaging studies of Tourette's patients who are suppressing their tics,abnormal activity has been consistently observed in the caudate and

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Studies have consistently shown abnormal activity in the caudate and prefrontal cortex in Tourette's patients who are suppressing their tics. These brain regions are involved in motor planning, inhibition, and control, and may play a role in the pathophysiology of Tourette's syndrome.

In Functional Brain-Imaging Studies of Tourette's Patients Who Are Suppressing