Bupivacaine and ropivacaine are look-alike/sound-alike drugs.Adverse drug reactions (ADRs)can occur if a clinician confuses these two drugs.Both drugs promote nerve conduction blockage analgesia when given locally,but bupivacaine is cardiotoxic.When selecting a local anesthetic to fill an elastomeric pain pump,what is one contraindication that should be considered?

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Lidocaine,bupivacaine,and ropivacaine all have similar actions.They are contraindicated in patients with hypersensitivity to amide local anesthetics.Compared to other local anesthetics,bupivacaine is markedly cardiotoxic.However,ADRs are rare when it is administered correctly.Most ADRs relate to systemic exposure,such as with pain pump failure.Systemic exposure to excessive quantities of bupivacaine mainly results in central nervous system (CNS)and cardiovascular effects.CNS effects may include nervousness,perioral tingling,tinnitus,tremor,dizziness,blurred vision,confusion,dyspnea,apnea,light-headedness,and loss of consciousness.

Bupivacaine and Ropivacaine Are Look-Alike/sound-Alike Drugs