A number of symptoms and signs are well-established manifestations of thyroid dysfunction.The American Association of Clinical Endocrinologists (AACE)has established practice guidelines for the diagnostic evaluation and screening of hyperthyroidism and hypothyroidism.The AACE recommends the ___________ as the single best screening test.A history of ___________ are symptoms of concern,and patients with ___________ require MRI or CT imaging,because this may be indicative of metastasis.Select the clinical triad to complete this diagnostic screening guideline.
A) serum TSH; calcifications; cough
B) thyroxin profile; whole-body radiation; Hashimoto's disease
C) free thyroid hormone levels; thyroiditis; a fixed immobile neck mass
D) TSH assay, neck or ear pain, dysphagia

Question

Quizplus · Accepted Answer

The AACE practice guidelines for the diagnostic evaluation of hyperthyroidism and hypothyroidism recommend TSH assay as the single best screening test.A thorough history and physical is indicated in screening for thyroid cancer.A history of being exposed to neck or whole-body radiation or being raised in iodine-poor areas should be assessed.A rapidly expanding neck mass,new onset of hoarseness,neck or ear pain,or cough are symptoms of concern.Patients with a fixed,immobile mass and/or hoarseness,dysphagia,or respiratory symptoms require CT or MRI imaging as part of the evaluation.These symptoms may be indicative of metastasis.Serum TSH measurement is the single most reliable test to diagnose all common forms of hypothyroidism and hyperthyroidism,with high sensitivity (98%)and specificity (92%).

A Number of Symptoms and Signs Are Well-Established Manifestations of Thyroid