In which disease or disorder does genomic imprinting operate on the sex chromosomes?

Question

Quizplus · Accepted Answer

Genomic imprinting operates on the X chromosome in fragile X syndrome. It is a genetic disorder caused by a mutation in the FMR1 gene located on the X chromosome. The mutation affects the expression of the gene and is subject to genomic imprinting, where the expression of the gene depends on which parent passed on the X chromosome. Imprinting can also occur on the autosomes, but in this case, the question specifies the sex chromosomes.

In Which Disease or Disorder Does Genomic Imprinting Operate on the Sex