Penicillins, cephalosporins, monobactams, and carbapenems all have what ring in their structure that is responsible for inhibiting the transpeptidation reaction, resulting in bacterial lysis and cell death?

Question

Quizplus · Accepted Answer

The active moiety of b-lactam antibiotics is the four-membered b-lactam ring-a ring structure found in penicillins, cephalosporins, monobactams, and carbapenems.The four-membered ring represented by the structure labeled b-lactam functions as a structural analogue of the normal substrate, and inhibits the transpeptidation reaction, resulting in bacterial lysis and cell death.

Penicillins, Cephalosporins, Monobactams, and Carbapenems All Have What Ring in Their