Nevoid basal cell carcinoma or Gorlin syndrome predisposes individuals to basal cell carcinomas and is due to increased activity in a signaling pathway.Which signaling pathway is activated and which component of the pathway is usually mutated?
A) WNT, BETA-CATENIN
B) NOTCH, HES1
C) SHH, PTC1
D) BMP, NOGGIN
Correct Answer:
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