During the process of endochondral bone differentiation,chondrocytes differentiate to ultimately form the hypertrophic chondrocytes.Each stage of chondrocyte differentiation is characterized by the expression of distinct matrix molecules.Which matrix molecule defines and is characteristic of the hypertrophic chondrocyte?

Question

Quizplus · Accepted Answer

Collagen Type X is a matrix molecule that is characteristic of hypertrophic chondrocytes. Aggrecan and Hyaluronan are characteristic of early chondrocytes, while Collagen Type II is found in both early and mature chondrocytes. Collagen Type I is not typically found in cartilage, but is a major component of bone.

During the Process of Endochondral Bone Differentiation,chondrocytes Differentiate to Ultimately