A researcher interested in patterning of the early neural tube identifies a new secreted factor expressed in the isthmus signaling center.Assuming that the newly identified factor plays a role in patterning,which axis of the developing neural tube would you expect to be perturbed if this factor is inactivated?

Question

Quizplus · Accepted Answer

The isthmus signaling center is crucial for patterning along the cranial-caudal (anterior-posterior) axis of the developing neural tube, influencing the development of midbrain and hindbrain structures. Inactivating a factor expressed in this region would likely disrupt cranial-caudal patterning.

A Researcher Interested in Patterning of the Early Neural Tube