A child is diagnosed with Treacher Collins syndrome,which results from a mutation in the gene TCOF1 encoding the protein TREACLE.What embryonic tissue is the most affected by this mutation?

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Treacher Collins syndrome results from a mutation in the TCOF1 gene, which encodes the protein TREACLE. This protein is involved in the development of the craniofacial region, which is derived from neural crest cells. Therefore, the mutation affects neural crest cell development, leading to the characteristic facial abnormalities seen in individuals with Treacher Collins syndrome.

A Child Is Diagnosed with Treacher Collins Syndrome,which Results from a Mutation