A child is diagnosed with DiGeorge syndrome due to a 22q11.2.1 deletion encompassing approximately 30 to 40 genes.Researchers have genetically inactivated these genes in mice to identify which are essential for pharyngeal arch development.Which two genes in the deleted area are now thought to be the key players in DiGeorge syndrome?

Question

Quizplus · Accepted Answer

According to the given information, researchers genetically inactivated genes in mice to identify which ones are essential for pharyngeal arch development. Therefore, the two genes that are now thought to be key players in DiGeorge syndrome are likely to be the ones that impact pharyngeal arch development. The two genes in the deleted area that are known to play a significant role in pharyngeal arch development are TBX1 and CRKL, making choice B the best answer.

A Child Is Diagnosed with DiGeorge Syndrome Due to a 22q11.2.1