Mutations in the growth factor SONIC HEDGEHOG would be expected to result in which birth defect?

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Mutations in the growth factor SONIC HEDGEHOG are known to cause the birth defect holoprosencephaly, which is a disorder of forebrain development that can result in a range of facial and brain abnormalities. Cleft lip and cleft palate are typically caused by a combination of genetic and environmental factors, while craniosynostosis and mandibulofacial dysostosis are caused by mutations in other genes.

Mutations in the Growth Factor SONIC HEDGEHOG Would Be Expected