Transgenic and gene targeting approaches have played important roles in understanding lung development and branching morphogenesis.Using this approach,Fgf signaling was blocked in the developing respiratory tree.What was the outcome of this experiment?

Question

Quizplus · Accepted Answer

Blocking Fgf signaling in the developing respiratory tree would result in the failure of branching morphogenesis, which is a critical process for the proper formation of the lung structure. This would lead to the lungs not developing properly and potentially causing respiratory problems or even death. Tracheoesophageal fistula or esophageal atresia are not directly related to Fgf signaling, and cystic fibrosis is a genetic disorder that is not caused by blocking Fgf signaling.

Transgenic and Gene Targeting Approaches Have Played Important Roles in Understanding