Researchers have shown that the HoxA and D complex of transcription factors,which are expressed in nested domains within the limb bud,are essential for outgrowth and normal patterning of the limb bud.This is clearly shown by the genetic inactivation of Hoxa11 and Hoxd11.In the forelimb,which structure(s)is/are affected?

Question

Quizplus · Accepted Answer

The forelimb consists of several structures, including the humerus, radius and ulna, carpals, metacarpals, and phalanges. Genetic inactivation of Hoxa11 and Hoxd11 affects the normal patterning and outgrowth of the limb bud. This suggests that these genes are essential for the proper development of the limb. Based on this information, the best choice is B, as the radius and ulna are part of the limb bud and are therefore likely to be affected.

Researchers Have Shown That the HoxA and D Complex of Transcription