What is the most significant criticism of the gene-crime relationship?

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The most significant criticism of the gene-crime relationship is that it is largely based on inadequate research designs and weak methodologies. Many studies that have been conducted in this area have suffered from small sample sizes, inconsistent measures of criminal behavior, and questionable measures of genetic factors. As a result, the findings are often not replicable, and many researchers have concluded that the gene-crime relationship remains largely unproven.

What Is the Most Significant Criticism of the Gene-Crime Relationship