A 47-year-old woman presented with painful ulcers and white lesions on her gingiva, tongue, and buccal mucosa of 6 months' duration. Biopsy of one of the white areas showed hyperkeratosis, basal cell destruction, and an intense lymphocytic infiltrate subjacent to the epithelium. This patient most likely has:

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The biopsy findings of hyperkeratosis, basal cell destruction, and an intense lymphocytic infiltrate subjacent to the epithelium are characteristic of lichen planus. Lichen planus often presents with painful ulcers and white, lacy lesions on the oral mucosa.

A 47-Year-Old Woman Presented with Painful Ulcers and White Lesions