A 55-year-old man presents with a 1 ´ 1 cm white lesion of his edentulous alveolar ridge. The clinical differential diagnosis should include:

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Frictional hyperkeratosis is a common white lesion that can occur on an edentulous alveolar ridge due to chronic irritation and trauma from dentures or other oral appliances. Lichen planus and hairy leukoplakia are less likely in this scenario, as they typically present with widespread lesions and are not specifically associated with the alveolar ridge. Ectopic lymphoid tissue is also an unlikely diagnosis, as it typically presents as a painless mass rather than a white lesion.

A 55-Year-Old Man Presents with a 1 ´ 1 Cm