A 15-year-old patient was found to have a 2 ´ 3 cm multiloculated radiolucent lesion of his mandible. At the time of surgery, a solid, bloody lesion was removed. Histologically, it was composed of benign-appearing fibroblasts and multinucleated giant cells. This is most likely which of the following?

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The multiloculated radiolucent lesion in the mandible, along with the presence of benign-appearing fibroblasts and multinucleated giant cells, is indicative of a central giant cell granuloma. These lesions are typically benign but can be locally aggressive and present as solid, bloody lesions on surgical removal. Peripheral giant cell granulomas, on the other hand, typically occur in the gingiva and do not involve bone. Hemangiomas are vascular tumors and osteosarcomas are malignant bone tumors, neither of which are consistent with the histological findings described. Osteoporotic bone marrow defects are benign, incidental findings that do not typically require treatment.

A 15-Year-Old Patient Was Found to Have a 2 ´